Hmm I wonder why then it has already happened with long duration and deep knockdown effects? Do some research before sounding off.
Part 2---What's this thing really worth?
Admittedly I own ISIS and have been jealous of ALNY's meteoric rise. But seriously read, the Part 1 post of all the premedication required for ALNY lead drug. It's pitiful. It's embarrassing. It's laughable. If you look at the price-volume it's clear that some type of manipulation is going on. I'm not smart enough to know if ISIS is being manipulated by HFT or ALNY is being manipulated by some tribe/mob. And I know that the market can behave irrationally longer than I can remain solvent. But at some point ALNY will come to earth. I think it's worth $1B. In a bubble it's worth $3B. It's way over valued.
Sentiment: Strong Sell
All subjects will be premedicated prior to dosing with ALN-TTR02 or placebo to reduce the potential for an infusion reaction. Premedication will be administered as follows:
Oral 8 mg dexamethasone administered the evening before dosing and 20 mg 30 to 60 minutes prior to start of infusion of ALN-TTR02 or placebo;
Oral 500 mg paracetamol the evening before dosing and 30 to 60 minutes prior to the start of infusion of ALN-TTR02 or placebo;
Oral H2 blocker (i.e., ranitidine 150 mg or famotidine 20 mg or equivalent other H2 blocker dose) the evening before dosing and 30 to 60 minutes prior to start of infusion of ALN-TTR02 or placebo;
Oral H1 blocker, 10 mg cetirizine (hydroxyzine 25 mg or fexofenadine may be substituted if subject does not tolerate cetirizine) the evening before dosing and 30 to 60 minutes prior to start of infusion of ALN-TTR02 or placebo;
Sentiment: Strong Sell
RNAi works! It works on cell lines but not the whole body. Think about the food we eat, it contains a lot of RNA. None of the RNA works as drug because it breaks down before got absorbed in intestine. How about injection? Unfortunately, it does not go into celsl either because the blood vessel wall. Delivery is the key. The human trials will continue for several more years.
No product, no profit, loss every single quarter from 2002 but alny keeps going up and up. Management feeds investors with PR all the time and management team rakes in hundred million dollars.
WHAT MAKES SENSE TO INVEST IN THIS KIND OF STOCKS? FOR WHAT?