Remember that before FOLD made a bigger commitment to develop their own ERT's, they were working toward doing combination studies with migalistat and the existing Fabry ERT's on the market. Migalistat as a single agent only works with 30%-50% of "amenable" Fabry patients (those whose bodies create some form of the enzyme, but it doesn't function well, vs non-amenable patients that produce no enzyme and have to be on ERT), but given that migalistat is showing that it may improve cardiac function vs ERT, this may open the door for doctors to prescribe migalistat off-label to the non-amenable patients on ERT in a combination therapy.
I sold the PUT instead of buying them. Have to take advantage of the high PUT premiums. Buying PUT are for suckers.