They probably made a copy of Everidge but moved one molecule into a different orbital, position, isomer or stereo-isomer.
These big pharmas are not to be messed with.
Unless CRIS has a chance to file a patent lawsuit.
The game is over for the Hh pathways.
"Tumors shrank or disappeared completely for eight or more weeks in four study participants, including three adults, following vismodegib treatment. In 13 patients, or 41 percent of participants with SHH medulloblastoma, disease stabilized and tumors stopped growing for as long as 17 months during vismodegib therapy.
The findings led to the drug being included in the St. Jude clinical trial for newly diagnosed pediatric medulloblastoma patients aged 3 to 22 years old. Patients with SHH medulloblastoma receive vismodegib as maintenance therapy.
Just out in Medexpress:
"A targeted therapy already used to treat advanced skin cancer is also effective against the most common subtype of the brain tumor medulloblastoma in adults and should be considered for treatment of newly diagnosed patients, according to research led by St. Jude Children's Research Hospital.
The drug, called vismodegib, is designed to block a key protein in the sonic hedgehog (SHH) signaling pathway. The pathway is normally active during fetal development and is inappropriately switched on in about 30 percent of medulloblastoma tumors, including about 60 percent of tumors in adults and 25 percent of tumors in children."
Does not matter Er will be off patent and CRIS will receive zero royalties - Party's over Cheerleader.
Anybody know about Erivedge being tested for refractory or resistant myeloid leukemia, myelodysplastic syndrome and myelofibrosis? I saw an article that it is entering 5 clinical phase II trials mostly done by academia (univ of california san deigo) and they saw positive effects in Ph1 trials. Any ideas? or is it "noise"? I just saw this today and the news is new.
go buy a car and treat yourself my friend. We are all in this to profit. If you did well then good for you. With grace I also did not do poorly this year so far overall. good luck.
Quack, Quack ducky shorted twice at $3.57
My posts are public and I am certainly not cooked
Thanks for the $1 / share in profits this year longs
Things we would like to hear in August by major CRIS cheerleader.
Your goose is cooked.
Stick a fork in it.
This steak is well done.
When big pharma sneezes, CRIS catches flu.
Major Manipulation by MM.
1. Curis has met with FDA regarding an end of study meeting regarding its orphan candidate for DLBCL patients; enrollment will commence for phase 2 in September.
2. Phase 1 combination study with Rituxan and 907 shows solid preliminary results.
3. Phase 1 solid tumor trial results shows promise of 907's broader application.
4. IND filing for PD-L1/PD-1 inhibitor is imminent.
too early to worry about these two actually. blrx has had a setback that the shorts are taking advantage of but nothing too much to worry about. I did not add any today but did not sell any either. cris....is a bit different after the recent postings by bent about the novartis drug approval. dont know how this will react in the short term. good luck.
Today @ 6.00
I had a 5k Buy order in at Close @ 3.30 seen some go by.
But the Crooks did not fill mine.
Sentiment: Strong Buy