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Alimera Sciences, Inc. (ALIM) Message Board

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  • Reply to

    What will happen with today's news?

    by spre1975 Jun 30, 2014 8:11 AM

    afterwards, PSDV has jumped 15 percent during the last week. ALimare has dropped one percent. There should be room for some gains here .

    Sentiment: Strong Buy

  • Reply to

    What will happen with today's news?

    by spre1975 Jun 30, 2014 8:11 AM

    yep and down almost 4 percent. The trade of Alimera never stops surprising me :-(

  • who knows?! It looks good.

  • Food safety is an unsolved problem with an estimated 48 million foodborne illnesses occurring each year and costing over $50 billion.

    PURE Bioscience is revolutionizing food safety with their heavily patented “SDC” and is positioned to become a leader in the food industry.

    SDC has already been tested in several large restaurant chains and the results were significantly superior to all other methods. SDC is a powerful and extremely effective antimicrobial but it is safe to humans and has been granted the EPA’s safest product classification of a category IV.

    LARGE RESTAURANT CHAINS are placing reorders that are expected to continue to increase to very sizeable numbers. PURE believes this is a 1.5 billion dollar market and SDC is far ahead of the competition.

    Based on meetings with the USDA and the FDA, FOOD PROCESSORS are expected to be using SDC in 2015 to decontaminate produce and meat. SDC will also extend shelf life as well as reduce manufacturers costs. PURE believes this is billion-dollar market.

    No other product can do what SDC does and do it safely.

    SDC will dominate antimicrobials in hospitals, schools, homes, offices, markets, public places, cruise ships, airplanes, trains, personal products like soaps and everywhere the public gathers. Antimicrobial market for disease protection such as influenza, MRSA, etc. is another multi-billion dollar market

    SDC is perfectly safe and it continues to kill dangerous pathogens for 24 hours EVEN AFTER IT DRIES.

    PURE Bioscience is on the verge of delivering very large and fast growing revenues beginning this year and shares are trading between $1.10 and $1.20 with a very small market cap of $32 million.

    All this information can be confirmed on YAHOO FINANCE under “PURE”

    PURE is a Strong Buy and Hold

    Sentiment: Strong Buy

  • Alimera closed on red numbers today, even after the green light in Italy for its intravitreal implant check this out http://finance.crwe-pr.com/2014/06/24/alimera-sciences-alim-agenzia-italiana-del-farmaco-oks-intravitreal-implant-for-chronic-diabetic-macular-edema/

  • Reply to

    ALIM earning call tonight

    by gerardfraser May 8, 2014 11:14 AM
    gerardfraser@rogers.com gerardfraser May 8, 2014 5:50 PM Flag

    ILUVIEN® Revenue Up Over 120% Sequentially from Fourth Quarter of 2013 well its better than nothing

  • It's bought out by a danish company after FDA approval of its drug. Could this happen to ALIM since its drug has already been approved in many EU countries?

  • Maryland, just curious why you post this on the ALIM MB? Biosilicon has very little to do with ALIM, it's a pSivida owned technology. It's good. It will be a game changer in the eye space and in other applications that need biologic sustained delivery.

  • Purpose:
    The purpose of this work was to exploit the tunable
    properties of BioSilicon (a form of oxidized porous silicon) as a
    substrate to provide long term release Bevacizumab (Avastin).
    BioSilicon can be manufactured with varying pore size and high
    surface area. Proteins including antibodies, adsorb by a combination
    of electrostatic, Van der Waals, and hydrophobic forces, while
    changes in surface hydration, entropy, and protein structure (shape
    and size) are also important. Strong electrostatic forces on the surface
    not only enable the antibody to adsorb but also subsequently desorb
    from the surface. In this work we evaluated the effect of pore size on
    Avastin release over a period of three weeks

    Methods:
    Oxidised porous silicon (OPS) was prepared with pore
    sizes ranging from of 10 to 100nm (the hydrodynamic radii of
    Avastin monomer estimated to be ~ 14.52nm). 5mg of OPS was
    added to 25μL of a 25mg/mL Avastin stock solution (prepared from
    the commercial formulation) and allowed to equilibrate overnight
    at room temperature (22.5οC). 1975μL of Phosphate buffer saline
    (PBS: pH7.4; 37οC) was added to the equilibrated OPS particles.
    The suspension was then hand mixed for 10 seconds and centrifuged.
    1mL of PBS was taken to calculate post loading concentration and
    1mL of PBS was freshly added to the dissolution pot. Sampling
    was performed every 24hrs for 20 days. Samples were analysed by
    Size-Exclusion Chromatography coupled with UV and fluorescence
    detectors.

    Results:
    Maximal adsorption was obtained with OPS of average pore
    size 25 to 30nm which provided approximately 12% (w/w) loading,
    larger pores gave slightly less loading (10% at 50nm and 8% at
    100nm) due to lower surface area. Material with a pore size of 10nm.

    Sentiment: Hold

  • Reply to

    Long slow decline until fda date

    by spre1975 Apr 16, 2014 7:16 AM

    Same thoughts here. The Q1 result won't be good and that would be disclosed in about two weeks. the $35 million debt financing had already given us some clue to where the figure would be.

    The NEW NDA will also be disclosed in the new 10-Q. the indication will be a much narrowed sub group. given the fact that all major indexes are at historical highs, a 50% hair cut is minimum. Remembering EXEL?

  • PURE Bioscience (PURE) found a new use for biotech that can quickly and safely kill pathogens that are dangerous to humans such as MRSA, influenza, HIV, E.coli, Salmonella, Norovirus, Hepatitis, Pneumonia, colds, Polio, deadly fungus, and most common infectious diseases.

    AND THE SOLUTION IS SAFE, FAST, CHEAP AND EASY.

    PURE Bioscience developed HEAVILY PATENTED “SDC” THAT KILLS ALL THE ABOVE-MENTIONED PATHOGENS AND YET IS PERFECTLY SAFE.

    SDC is Silver Dihydrogen Citrate that has been infused with negative ions.

    IT IS SIMPLY WIPED OR SPRAYED ON ANY SURFACE AND IT REMAINS ACTIVE FOR 24 HOURS.

    Over 650 restaurants tested SDC on more than 1,000 data points and compared the efficacy of the chain's current sanitizer with that of PURE Hard Surface disinfectant and sanitizer and SDC was OVER 90% MORE EFFECTIVE.

    SDC has also been successfully tested for food processing of meats and produce to destroy the dangerous pathogens such as E.coli, Salmonella, Norovirus and others and is expected to set the standard in the food industry.

    THE EPA CLASSIFIES SDC WITH THEIR SAFEST RATING OF CATEGORY IV.

    Also important is that SDC does not cause these dangerous pathogens to become resistant like antibiotics.

    The World Health Organization estimates the cost of influenza epidemics to the economy at $71-167 billion per year.

    The CDC estimates that each year, 48 million food borne illnesses from contaminated foods result in over $50 billion in losses from 128,000 hospitalizations, 3,000 deaths and very costly food recalls and lawsuits.

    SDC will appeal to large markets such as the cruise industry, air travel, all public transportation, schools, hospitals, sporting events and essentially ALL PUBLIC PLACES.

    SDC SALES ARE POSITIONED TO EXPLODE and PURE shares are only $1.20.

    Sentiment: Strong Buy

  • Reply to

    Long slow decline until fda date

    by spre1975 Apr 16, 2014 7:16 AM

    Could go down even more after that. FDA is a captured, pay-to-play agency. If Apple, Amazon or Netflix had to go through an FDA-type agency how do you think that would have worked out? They would have never made it because the GE's, IBM's and CBS's of the world wouldn't have it. That's the environment small drug companies have to deal with at the FDA even if the drug has proven beneficial in other places in the world.

  • Out. Will buy back in late Aug at 3.xx again.

  • 6 months review was expected due to facilities deficiency in CRL -- if this reaction is due to that its unwarrented.

ALIM
5.91+0.06(+1.03%)Jul 11 4:00 PMEDT

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