No problems with approval
The TLR science has been proven valid.
The presence of Merck, GSK and AstraZ ALL validate that the TLR science is genuine.
GSK, Merck, AstraZ Become prospective Buyers or royalties will be
In a video on TheStreet web site (The Next Big Thing in Biotech: Dynavax), Adam F mentions an issue regarding manufacturing rights to a component in Heplisav that is controlled by GSK and Merck. Does anyone know if the status on this issue?
Is 700 million the round number they are looking for after the drug is approved? Is this the number most people are using to guestimate a PPS at that point? I'M sure it will be much higher after the drug makes it over seas. However just looking for a general consensus of what folks are using as a number for an initial pop on the US market.
Sentiment: Strong Buy
Without A control arm I believe there is only a month in the interim between first and second shots and the 1 year follow up should commenced.
The FDA should be willing to allow for interim analysis of the safety data.
We should get A peak at the safety data soon .
If VRBPAC is preserved on video, give a watch/listen. That was a shocking moment as Martin completely stumbled.
I thought the 1 year follow up was done for the 2nd phase III, but not for the 1st phase III. Isn't that right?
BIG :-D ?? Well, step right up to the show, under the big op the master of cereMONIES Mr. Eddie will be happy to relieve you of some of that in return for some world-class entertainment only rivaled by that brought to you by the previous master of cereMONIES Dr. Dino.
Just so's ya' knows, jigga.....
I did have a house on the market recently.
I finished it right around July 4th, we put it on the market July 7th.
We closed on the sale in late September. Cha-Ching!!! (BIG :-D )
We are already making bids on prospective new "contenders".
"And if ya' din't know, now ya' knows, ya' knows, ya' knows........jigga!" (word to biggie)
P.S. How's things in old limey town? You been hanging with "old sir witless", king gorilla of G_reedy S_inful K_riminals?
BECAUSE, "enquiring minds NEED to KNOW"!
How's that grab ya?
Just to be safe and clear, if I was wearing a thong in your dream, then you having the WRONG dream of me. Just, plain wrong. Just sayin.......
Once again, another gem by the mighty black raven right on que You prove my point once again. You're nothing but a wannabe clown investor with a big mouth and no bite. Only someone who is completely blinded by their own stupidity and failure would attempt to make the kind of comparison you are making here, much like many of your posts on this board. With the brains you possess, it no surprise to me that you've taken the losses you've sustained investing and why you continue to post nonsense like you did here. Funny thing is I know you actually believe what you post.....portraying your self to be a knowledgeable investor who knows how to get a return on an investment when in fact, you clearly don't know #$%$.
So now here you are attempting to compare DVAX, a drug manufacturer, to EGLE, a shipping company. Wait, didn't you try to do the same thing a few months back with another shipper in NEWL when it was doing the same thing EGLE is doing now? So you think EGLE, with its 290MM market cap and 1.2B total debt, is comparable to DVAX with its 390MM market cap, 154MM in cash and 0 debt? Wow. Now I know why you're known as the mighty black raven (btw all ravens are black fool). Oh yeah, EGLE filed for chapter 11 a few months ago sealing its fate while DVAX completed heplisav PIII enrollment 3 months ahead of schedule and just initiated pI/II trial of another candidate in SD-101.
If we went by the world's definition of who We are supposed to be because We appear weird...
'Well, surely, this guy can't have a productive life, surely, he doesn't have a sense of humor. Surely, he can't love life.'
We stereotype people in this world. And so... if the world thinks you're not good enough, it's a lie, you know.
Get a second opinion.
Did you buy back in ?
Outboard Jack is talking about going sailing, and blackraven is talking my head off about his real estate, about his house he sold\bought, about his Vietnamese wifey, and his kids. And I am like: what the heck? why do I need to know this..?
Looks like the efforts to contain Ebola on "the dark continent" and off the shores of other civilization, have failed pretty much miserably.
Now in Africa, America, Spain and 1 case in France , last I heard. Almost 5K dead.
My bet is that the doofus at the helm of the CDC (friedrich, or "fried-rice") gets canned. He CLEARLY is NOT on top of the situation here in any form and more often than not he inserts foot into mouth at the podium.
Ebola will get him, but not as an illness casualty; ebola is a bigger problem than he can handle and it's painfully obvious that he is "incompetent below his paygrade".
It is truly scary to realize how easily this can spread and get out of hand.
With only a few cases here it's easy to use the blood of survivors to help conquer the problem; but if the number of cases begins to climb there may not be enough survivor blood out there.
I think that I heard that Kent Brantley fellow (Dr.) has donated over a gallon of blood in transfusions thus far.
That is actually a lot; most donors cannot donate again for 8 weeks from any donation.
I figure that they are bending the rules there for his case (to save others), but he has to be careful, because donating too much does take a toll on the body, in terms of fatigue.
Hopefully, they (health regulatory people) can keep this in hand for all of our sakes. May God be with us all here in this dangerous time.
A sad story from the naked city.
If it happens to you, "don't be like that version of Rob Lowe" (from a Dish commercial).
THINK, BEFORE, you sell:
sub3111 • 4 hours ago Flag
Can anyone help us? My wife and I have an account with Tradestation for day trading and options trading. This morning I got up and started the computer and logged into Tradestation. Being a day trader and options trader, I saw that EGLE was up a ridiculous percentage. I immediately went and checked to see that we had 3000 shares! I immediately began selling at almost any price I could get and went to tell the wife that we could celebrate. When the market opened I went to look and they showed that we were now 2500 shares short . I called them and they said it was my problem, and that I should read the news. When something like this happens, shouldn't a company who want the business of day traders to keep their clients accounts updated for when the pre-market opens. I see where they made the changes at 9:15 am
Don't forget: "He called them and they said it was HIS problem" (owing the shares back that he no longer had).
Don't be like that sad version of Rob Lowe........
An American dry bulk shipper; big boats; like Dry Ships (DRYS) or Diana Shipping (DSX), based in NY.
They had been struggling, the stock was like, at 10 cents to no more than $1.50 in recent days.
Same old, same old. This morning, investors woke up to EGLE being UP some ridiculous number like 1500% - 2000%. Many thought that they had struck it rich, "3 feet from gold" and on and on.
So the morning news was EGLE halted around 9:30-10:30AM for news. No news for hours.
The most recent news had been that EGLE's management had been granted a BK on restructuring which they had filed for.
In true form, the "management" released the news in afterhours of their restructuring and investors ended up waking up to the reality that their "struck it rich" had become BOHICA (bend over, here it comes again!).
Reverse split to the tune of like 1 share for 100 or 200 or 300.
Some investors had told tales of having like 3000 shares (yesterday) and later today, 30 shares.
No celebration, no party; just big OUCH,
The rats found a way to stay alive once again.
I've never understood how that kind of thing can survive; these shipping companies with giant ships and tiny stock prices. The ships SHOULD be worth more than the stock price or the company, but I suppose that they DEBT on the ships factors in there somewhere as well.
Anyways, there is another example of what you might see happen here. R/S locked and loaded; you wake up one morning and think that you're less than "3 feet from gold". "Struck it rich!" Booze cruise and celebration!
Well, guess again.
Keep an eye on EGLE and just watch what happens to that $15 stock price of today.
I bet that before the end of the year, they are much closer to $1 than $20.........
"That hadn't been Performed"
It was more like " UHA, I don't know"
It was a Sad Day for sure*