The following comments from the press release are encouraging and indicate that the potential for positive catalysts may not be that far down the road:
"We have already made extensive preparations for both trials, including design of the protocols and identification of CROs (clinical research organizations). Given the encouraging results of the previous trial, clinicians are keen to work with us to enroll patients quickly. We look forward to continuing to work with the FDA on the regulatory review and to sharing INTERIM DATA from these studies in a timely fashion."
Hmm....interim data on the short trial which ends in the first half of 2016 means that we will probably get the interim data in short order, probably in less than a year from now. What would happen to the stock price if more positive comments from patients emerge on the NTM forums? There could be a run-up in anticipation of confirmatory results.
There is a reason that I keep the fringe element on both sides on "ignore." Both deny the principles of medicine for emotional reasons or ignorance. Arikayce will have a huge market for NTM because there are no treatments that are predictably effective. The Phase IIb study, which got marginal results was conducted on patients who had been treated for years with therapies that did not work (i.e., were not efficacious in eliminating NTM). Now they have a treatment that got rid of the infection in more than 50% of the patients who were previously "incurable" (cure = no NTM on culture). What medicine tells practitioners is that if you have a better therapy and use it sooner, the patients will benefit. What were the words of the chronic NTM (M. abscessus patient?) I think I could get rid of the infection if I had further access? He is correct. But lets us see if the Phase III included patients that have not had to endure the treatments that are ineffective. Any doctor would tell a patient, the earlier we get you on the best treatment, the lower the risk and the better the chances for efficacy.
INSM will replace the COO in short order, but they do not have to replace the CMO in a hurry. They are not even advertising for a CMO. Why, Dr. Kenneth Olivier. He is the key to NTM and the next two years of INSM progress. The path forward is clear for anyone experienced in FDA regulatory submission or the principles of medicine.
Sorry terry, you are among the ignorant here and the "posse" has you pegged.
I can't find it, but is Insmed going to be in a Pharmaceutical conference in San Diego in Sept/Oct?? There was a lot of stuff deleted over the past few months. Sorry if I'm not remembering correctly.
The market is clear for NTM and the revenues will be significant. But the most important aspect for treatment of this disease will be the fact that people with chronic NTM (like the poster who has had M. abscessus for years) will be treated straight away with Arikayce and not have to endure inferior treatments for those initial years. This direct use of optimum treatment will also preclude exacerbations. I believe this company is going to expedite their efforts to get approvals all over the world. The positions they are recruiting and the cash they just raised suggests strongly that they intend to be a stand alone company in the future. I think 2016 will be the year.
The thing is, when someone creates all these clones/IDs and spews the many lies, pretending they are many of us....THEN they/he wants us to take his predictions serious? And then a few chime in and support him. Are they all one sick puppy (kinkey, kimlee, Kolob too??). So, for now, ignore (and I have many) is the best option or move to the "utter" board to avoid this. It does mess up the flow of communication though. Surprised he did not end up on the FOLD board yesterday because a bunch of loonies showed there too (just like here on June 18-20th). This Terry et al is no mental giant and his "blushing" gives me the creep.
Is`nt that the point who could keep track of all these clones and their multiple ID`s-- one click of the mouse and you might be shocked how many actual one ID posters there are on Yahoo. Or just Block all multiple ID subscribers,Yahoo could probably do that easier then adding a new feature to the message board.
Showing responses to your post to me,but when I open it there`s just your original post and my one response. It shows 7 replies,where are they? Are they all multiple ID users and Yahoo has decided to just block board use to all these individuals? That would work for me,get rid of all the bad eggs.
I FINALLY have a CLONE!!! From the CLOWN of San Diego. At least I have that going for me which nice.
It would only be a smart business move for Yahoo to protect the honest investor here, by allowing us to delete all of a posters user ID`s with one click of the mouse. Anyone using multiple ID`s is`nt an honest investor,in my book,I just hope Yahoo can understand that--these people are abusive users of their system and they need to help us get rid of them easier.
His posts are gone now. Anyway, despite the continued BIO downturn (even in a decent NASDAQ climate), we stood our ground. Not happy with mid $13's but will take it for now.
You would definitely be hurt if Yahoo implemented this idea maggot--- seems like hitting that button would get rid of you and your multiple ID`s on many message boards,including SIRI.