they've injected hundreds of thousands of stem cells into subjects and I haven't heard a negative thing concerning safety issues. That's big in and of itself. As for efficacy, we'll see. The best way to play biotech is to buy a basket of biotechs. Some will win, some will lose. When you win, the potential return can be very large, as with ACTC. End result, hopefully, will be huge profit. Some of my other holdings are: LXRX, SGMO, VICL, PSDV, CERS, FOLD, PSTI, GERN, CCXI, PRAN, NVIV, KOOL. Good luck to all...