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BioCryst Pharmaceuticals, Inc. Message Board

  • left2rightdoor left2rightdoor Apr 10, 2013 10:58 PM Flag

    Tamiflu resistance gene found in 3 H7N9 samples

    Bloomberg story out of Japan, at 10 Eastern.
    A gene mutation known to help influenza resist Tamiflu was found in the first of three H7N9 bird-flu patient specimens in China, sequence data show.
    The flu virus from the patient in Shanghai has a mutation known as R292K that causes high-level resistance to the Roche Holding AG (ROG) pill and reduced sensitivity to a related drug from GlaxoSmithKline Plc (GSK) called Relenza, genetic sequence information posted on the website of the Global Initiative on Sharing Avian Influenza Data show. Subsequent H7N9 specimens from a patient in Shanghai and one in Anhui province don’t show the mutation.

    Maybe the world needs a better antiviral

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