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Threshold Pharmaceuticals Inc. Message Board

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  • tredleon tredleon Oct 23, 2008 6:23 PM Flag

    While Today's "Encouraging" News...

    SMAC - you're the one who was pumping the pre-clinical/mice studies before and I kept warning you that the monotherapy studies for TH-302 were worthless. Go back to the slide show - TH-302 as a single agent always performed worse (in terms of "response" and survival) than the current standard of care chemo agent. But this makes complete sense - traditional chemo reaches the larger portion of the tumor feeding off of the vasculature, while TH-302 reaches the smaller hypoxic regions of the tumor. Neither treatment on its own can kill the entire tumor - it is only when they combined them that they showed the dramatic "cure" rates in the mice. Given the dultion that has been crammed down on shareholders, this will never be a home run, but you could get a decent chunk of your money back?

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    • One more thing: I am by no means trying to belittle anyone here. I lost 6 figures on this one. That was a tough one in my young, family life.

      I am only hoping that this f'ers read this message board once in a while and see how decimated they have left us. I see Slick and Powell have also lost quite a bit of money. 8 figures each, as far as I can see. THEY deserve it, IMHO. Not you, cancun, me, or any other poor sap.

      • 1 Reply to SMAC693
      • They´re gonna get you again SMAC! The feds! LOL!

        I´m down in this huge also. But still blind believer of their
        Hypoxia technology for the long run. I just hope their cash does'nt run out like in the past. As for the rest of the market I´m also doing fine so far. This is a very dangerous market and only intraday trading works out something. This is the only stock I´m keeping for the long term and even so I´ve taken some loss to trade other stocks. Sold half the reverse split day and I´ll buy them back in a less volatile market.
        This is the future for cancer treatments. Tred, good to read from you. Good luck!

    • I was excited by the slideshow before. I am totally deflated by the stock price now.

      Maybe this will work out in combo therapy.

      This 45 cents would have to go to $12 for me to get a "decent" amount of my money back. That's a tall order.

      I would not be surprised if Slick, Powell, Sutter, Tang, etc. decide to "take under" the company for $2-3 million. It's hard to believe these jokers just pumped $17 million into this company a month ago. You're telling me Powell and Sofinnova ALONE cannot support the stock price here???

      We shall see.

      My point is, since I have written this off as a total loss and have now had ENORMOUS success trading ETFs this year, I can sit back and laugh and the daily decline. I can't wait to see what happens when this hits a dime or less.

      Sorry if you've lost. I truly am. I had fed agents at my house because of this company, that's how mad I was. Now I just laugh. and think, wow, Slick has going to have some 'splainin' to do in the after life when we all meet our maker. I don't know how he looks at himself in the mirror everyday, Denise and Michael included.

4.07+0.09(+2.26%)Oct 2 4:00 PMEDT