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Threshold Pharmaceuticals Inc. Message Board

  • pharmajedi pharmajedi Mar 30, 2012 5:02 PM Flag

    lets' be honest

    The PFS results of 5 months of the higher dose were not as expected (I was personally expecting 6.5-7 months), however the RECIST response of 27% was impressive to me, from a dose response perspective as well as looking at the PFS of the lower dose. So the efficacy data of the high dose is not entirely blow out, but very good from a clinical perspective considering the very good safety profile. All the signals here point to a very clear and straight forward regulatory path and designing a pivotal trial, which Merck is paying 70% of all costs for...gotta luv it!

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