A business associate of mine is 92, has been very successful with investing, and never and I mean never sells a stock (unless of course they get bought out for cash). George had a chance to buy 10% of the Cincinnati Bengals in the early 1960's for $25,000 and he chose to pass on it - (this may have even been before Paul Brown bought them). Today, the Bengals are worth $970 million and are the 27th ranked value among NFL teams per Forbes. George would have never sold his 10% and if he had bought into them, I might be watching the games in style instead of from the cheap seats.
diaDexus = the Cincinnati Bengals except you won't have to wait 50 years for them to be worth 1 billion. Maybe less than 5 years with a successful darapladib outcome. In fact they could even be the Dallas Cowboys, the number 1 NFL valued team at over 2.5b.