thats the reason you sell on approval and short. the majority of money in this is in for the runup, once thats over its dilution till market and 99 percent of the time the market for product is nowhere near what they claimed. just back test fda approvals, over 90 percent of these small cap fda plays are lower after approval and actually much lower. get its the main reason its almost impossible to get shares to short after approval. shorting after approval is usually more profitable than buying before approval and you get the same returns much much faster. where affy may have took weeks to give you 25 percent, an approval short will give you in days or hours sometimes.