Tue, Sep 16, 2014, 5:51 PM EDT - U.S. Markets closed

Recent

% | $
Quotes you view appear here for quick access.

Vanda Pharmaceuticals, Inc. Message Board

  • mid_swe mid_swe May 21, 2010 5:12 PM Flag

    QT Prolongation the caus of failing sales?

    There must be a reason why sales are so bad? kampaa raised this topic on a different message board so I thought I would assist him here!

    "QT Prolongation: In an open-label QTc study in patients with schizophrenia or schizoaffective disorder (N=160), Fanapt was associated with QTc prolongation of 9 msec at an iloperidone dose of 12 mg twice daily. This affect was augmented by the presence of CYP450, 2D6 or 3A4 metabolic inhibition. The use of Fanapt should be avoided in combination with other drugs that are known to prolong QTc. Caution is warranted when prescribing Fanapt with drugs that inhibit Fanapt metabolism." : In an open-label QTc study in patients with schizophrenia or schizoaffective disorder (N=160), Fanapt was associated with QTc prolongation of 9 msec at an iloperidone dose of 12 mg twice daily. This affect was augmented by the presence of CYP450, 2D6 or 3A4 metabolic inhibition. The use of Fanapt should be avoided in combination with other drugs that are known to prolong QTc. Caution is warranted when prescribing Fanapt with drugs that inhibit Fanapt metabolism."

    http://www.pharma.us.novartis.com/newsroom/press-release.jsp?PRID=2260&usertrack.filter_applied=true&NovaId=4029461984501629387

    SortNewest  |  Oldest  |  Most Replied Expand all replies
    • "There must be a reason why sales are so bad? kampaa raised this topic on a different message board so I thought I would assist him here!"

      "QT Prolongation: In an open-label QTc study in patients with schizophrenia or schizoaffective disorder (N=160), Fanapt was associated with QTc prolongation of 9 msec at an iloperidone dose of 12 mg twice daily. This affect was augmented by the presence of CYP450, 2D6 or 3A4 metabolic inhibition. The use of Fanapt should be avoided in combination with other drugs that are known to prolong QTc. Caution is warranted when prescribing Fanapt with drugs that inhibit Fanapt metabolism." : In an open-label QTc study in patients with schizophrenia or schizoaffective disorder (N=160), Fanapt was associated with QTc prolongation of 9 msec at an iloperidone dose of 12 mg twice daily. This affect was augmented by the presence of CYP450, 2D6 or 3A4 metabolic inhibition. The use of Fanapt should be avoided in combination with other drugs that are known to prolong QTc. Caution is warranted when prescribing Fanapt with drugs that inhibit Fanapt metabolism."

      http://www.pharma.us.novartis.com/newsro...

    • Truth hearts!

 
VNDA
12.02+0.14(+1.18%)Sep 16 4:00 PMEDT

Trending Tickers

i
Trending Tickers features significant U.S. stocks showing the most dramatic increase in user interest in Yahoo Finance in the previous hour over historic norms. The list is limited to those equities which trade at least 100,000 shares on an average day and have a market cap of more than $300 million.