I've been using AGN products for years. The 1st is called Tazorac which is used for psorasis. Prices have gone up acroos the board on this cream. In the u.s. it's 137.50 per tube, in canada it's 65.00. Both prices have gone up yoy. Now Botox i was just injected with for TMJ, which also gives me massive migraine's!Bottom line is after 2 weeks no more migraine's, and jaw feels better. Now as far as costs goes, I ordered my AGN botox which for 50 units was 230.00 + 50.00 for dry ice shipping in canada, in the u.s. they will only fill 100 units for cosmetology purposes which runs 580.00 at CVS, wal mart doesn't carry botox! Oh ya, the most important part of this post is every single person I talked to about botox said use only AGN, all other cheap botox breaks down in 3 months vs. 6 months with AGN! I've been dating a gal that's a plastic surgeon, she's been floored with business as far as people spending $ on treating themselves, and i dont see it stopping!