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Astex Pharmaceuticals, Inc. Message Board

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  • kyjellie kyjellie Jan 31, 2013 11:11 AM Flag

    Batzem, what is your price target this year?

    Batzem,

    Generics are bioequivalent. Not necessary exact copies. My doctor the other day stated he cannot use the generic version of his choestrol drug, because the side effects are greater. Dacogen and vidaza have some serious side effects. Sometimes hospitalization. Can you show us where you found these master files?

    I appreciate your input. If a generic enters the picture, we will take a hit on shareprice. Our eyes and ears need to be watching out for this.

    Sentiment: Strong Buy

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    • Batzem,

      Here's a nice piece on generic's. Most of the article was pro generics, but they do point out this:

      Patients benefit from lower costs, but a generic substitute may not always be the best fit. For one, a generic drug's inactive ingredients often differ from those of the brand-name version, which may cause allergic reactions or other problems for a small percentage of patients.

      Also, patients may simply metabolize different drugs in different ways, said Sandy Walsh, spokeswoman for the U.S. Food and Drug Administration.

      But in general, patients shouldn't fear generics.

      "As far as the agency is concerned, they're approved to be exact copies," Walsh said.

      Still, when it comes to serious medical conditions, doctors say even the slightest change in a drug regimen may have negative consequences.

      Sentiment: Strong Buy

      • 1 Reply to kyjellie
      • KY = The fact is anybody can have an idiosynchratic reaction to any drug. (side effects) You can find stories where people do better on the generic than the brand, More than 70% of all scripts are substituted for with generics. If one comes we will lose most of our market share

        As for the your other question type in Drug Master File Decitabine into your browser. There are 4 approvals the first one in 1998 is the one Dacogen uses. The other 3 are from weill known raw materail suppliers to generic companies

 
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