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Astex Pharmaceuticals, Inc. Message Board

  • weightbayou weightbayou Feb 1, 2013 1:08 PM Flag

    AZD3293—Beta-secretase inhibitor (Alzheimer’s)

    AstraZeneca is Astex's partner
    This could be the biggest gem in Astex's pipeline.

    AZD3293—Beta-secretase inhibitor (Alzheimer’s)Beta-secretase, also called BACE1 (beta-site of amyloid precursor protein cleaving enzyme) or memapsin-2, is an aspartic-acid protease important in the formation of myelin sheaths in peripheral nerve cells and in the pathogenesis of Alzheimer’s disease. Inhibitors to block the action of this enzyme could prevent the build up of beta-amyloid, which may help slow the progression of, or stop, the disease.

    Sentiment: Strong Buy

 
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