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Astex Pharmaceuticals, AŞ Message Board

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  • kyjellie kyjellie Feb 5, 2013 4:06 PM Flag

    Novartis/LEE011

    These are both Ph2 trials. I like that Novartis is going after both kinds of mutant melanoma with LEE011. Also to remind you they just started a neuroblastoma trial also with LEE011. 4 trials with 3 of them just ramped up.

    Sentiment: Strong Buy

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    • More info on these kind of melanoma's:

      When melanoma is diagnosed early, it is generally a curable disease. However, when it spreads to other parts of the body, it is the deadliest and most aggressive form of skin cancer. A person with metastatic melanoma typically has on average a short life expectancy that is measured in months. The American Cancer Society estimates there will be more than 76,000 new cases of melanoma and over 9,000 melanoma deaths in the United States in 2012. BRAF and NRAS mutations occur in 50 to 60 percent and 15 to 20 percent of patients with melanoma, respectively.

      Sentiment: Strong Buy