I am not sure why anyone would want to tender their shares at $8.50? Small investors could easily get out over the last couple of days above the $8.50 and do not have to wait until the deal closes in a couple of months? Afew of the larger investors such as Aquilo and Sarissa's Denner also feel the price is too low and may be buying above the $8.50 price. Top executive of ASTX who worked out the deal with Otsuka own very few shares of ASTX. Anyone that wants to tender their shares at $8.50 should sell within the next few days and get a premium and cash quickly. I do not plan to tender my stock, however I will monitor price and volume.