I agree that Monday will be the day. I listened to their last presentation recently. They stated that the trial would be unblinded on Nov 15th, give or take a day. The 15th is Saturday so that would mean a Monday news release before the market opens. This is very typical of these types of events. Companies like to unblind over the weekend so as to eliminate the risk of a leak. Then the results will be released very early Monday morning, well before pre-market trading begins. This gives everyone a chance to digest the news. My guess is down 25-30 on bad results, and up 30-40 on positive results. This is going to be really wild. My bet has been placed on positive results.