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Puma Biotechnology, Inc. Message Board

  • rrtzrealmd rrtzrealmd Jul 23, 2014 12:32 PM Flag

    Smoke and mirrors...

    ...the level of ignorance regarding statistics and experimental design among investors is astounding...oh, look, a 33% in DFS...hurrah, hurrah!...ell, first consider that the control was DOING NOTHING AT ALL...gee, something is better than nothing by a whopping 33% -- I'm sooooooo impressed...

    ...and then there's that stinkin' disease free survival...that is essentially a MEANINGLESS statistic because it ignores everything else...what SHOULD be used is relapse free survival-- defined as the time to the first relapse or death from ANY cause, not including second primaries or other cancers...RFS takes into account other factors sensitive to a treatment's effect -- e.g.. therapy may have adverse effects beyond second primaries, such as heart failure, for example...

    ...but doing that would make biotech more honest and we wouldn't want that now, would we?...

 
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