AMGEN off the hook -all ESA's work the same way--no alternative--dose
All types of anemia are not the same. I doubt if there is a realistic alternative to ESA's in these life threatening circumstances. In nornmal doses these drugs do there job. Off-label experiments are just that. This class of drugs is needed.
Here is all you need to know.
"Because all ESAs work the same way, the findings from these studies apply to all ESAs; the FDA is reevaluating the safe use of this drug class," the advisory said.
The new, boxed warning states that ESAs increased the risk of death and serious cardiovascular problems when given at higher-than-recommended doses.