If linaclotide is like morphine then plecanotide is like tylenol #3.
People try to say plecanotide is better because it doesn't cause diarrhea. Has anyone paid attention to what they are trying to treat? Plecanotide doesn't cause diarrhea simply because it doesn't work as well. Lower efficacy and 2nd mover...plecanotide is going to be a minor player.