My entire portfolio is in biotech. This excludes all the money I have in IRAs, and in bank, but the money I use to play in the stock market is all in Biotech. My two biggest holdings are ONXX and SNTA with IMGN being #3 but that latter is only because PGNX took a nose dive. ONXX has been a rocket, and still has a way to fly. SNTA is not far behind.