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Aethlon Medical, Inc. Message Board

  • robert.vince robert.vince Sep 13, 2013 7:10 AM Flag

    Aethlon Medical Announces Dr. Douglas Taylor as Chief Scientific Officer of Exosome Sciences, Inc.

    Aethlon Medical, Inc. (AEMD), announced today that Dr. Douglas Taylor has accepted the position of Chief Scientific Officer at Exosome Sciences, Inc. (ESI), a wholly owned diagnostic subsidiary of Aethlon Medical. Dr. Taylor is credited with the discovery of tumor-secreted exosomes and is a leading published author on the topic. "We are truly honored that Dr. Taylor has agreed to lead our research endeavors at Exosome Sciences. His pioneering research has been instrumental in establishing an industry for exosome-based diagnostics and therapeutics," stated Aethlon Chairman and CEO, Jim Joyce. The news was first reported through a presentation given by Mr. Joyce at the Exosomes & Circulating Biomarkers 2013 Summit. Mr. Joyce's presentation occurred after the close of market hours on September 12th.
    \Aethlon Medical develops therapeutic devices to address unmet medical needs in cancer, infectious disease, and other life-threatening conditions. The Company is preparing to launch the first U.S. studies of the Aethlon Hemopurifier® as a therapy to address hepatitis c virus (HCV) based on the recent approval of an Investigational Device Exemption (IDE) by the United States Food and Drug Administration (FDA). The Hemopurifier® is a first-in-class device that targets the rapid elimination of viruses and cancer glycopathogens, including disease-promoting exosomes from circulation.

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    • Exosome Sciences was established by Aethlon to pursue exosome-based strategies to diagnose and monitor the progression of cancer, infectious disease and other life-threatening conditions. ESI's lead product, an Enzyme Linked Lectin Specific Assay (ELLSA) has been validated to identify the presence of exosomes underlying the human immunodeficiency virus (HIV), tuberculosis (TB), and various forms of cancer, including ovarian, melanoma, breast, lymphoma, and colorectal.

      Dr. Taylor stated, "I am extremely excited about joining Exosome Sciences as their Chief Scientific Officer. I have been pioneering the field of exosome biology for more than 35 years and believe that exosomes represent the ideal disease marker due to their stability in the peripheral circulation and ability to be multiplexed. Exosome-based diagnostics will not only be used in identification and management of a variety of cancers, but also in other pathologies such as viral infections, pregnancy complications, birth defects, cardiovascular and neurodegenerative diseases. No other platform exhibits their potential for patient stratification and real-time monitoring of therapeutic responses. I have a long history of collaboration with scientists at Aethlon Medical and this opportunity will expand that interaction to bring ELLSA based assays to the clinic."

      • 1 Reply to robert.vince
      • The release of exosomes by viable cells has been demonstrated in multiple cell types and systems. These nano-sized vesicles are detectable in biologic fluids, including blood, urine, ascites, and pleural fluids. They are essential mediators of normal homeostasis, based on their role in intercellular communication via surface interactions and transfer of macromolecules between cells. Cell injury or transformation is associated with alterations in the cell's exosome production and composition of these exosomes. This aberrant exosome composition can be utilized as surrogate markers of specific disease pathologies. The ESI mission is to advance an exosome-based biomarker platform to diagnose a broad-spectrum of disease conditions as well as monitor disease progression/regression in response to therapy as a means to improve patient management and outcomes. In the oncology field, ESI products will also be positioned to serve as companion diagnostics that determine when to initiate Hemopurifier® therapy or provide real-time monitoring of tumor responses to Hemopurifier® therapy.

 
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