This looks like a good joint patent between aveo and xoma.
United States Patent 8,273,355
Winston, Jr. , et al. September 25, 2012
Hepatocyte growth factor (HGF) binding proteins
The present invention provides a family of binding proteins that bind and neutralize the activity of hepatocyte growth factor (HGF), in particular human HGF. The binding proteins can be used as diagnostic and/or therapeutic agents. With regard to their therapeutic activity, the binding proteins can be used to treat certain HGF responsive disorders, for example, certain HGF responsive tumors.
Inventors: Winston, Jr.; William M. (Marlborough, MA), Wright; S. Kirk (Waltham, MA), Han; May (Brookline, MA), Breault; Lyne (Roslindale, MA), Lin; Jie (West Roxbury, MA), Etemad-Gilbertson; Bijan (Jamaica Plain, MA), Knuehl; Christine (Natick, MA), Gyuris; Jeno (Lincoln, MA), Horwitz; Arnold (San Leandro, CA)
Assignee: AVEO Pharmaceuticals, Inc. (Cambridge, MA)