Fri, Aug 1, 2014, 5:13 AM EDT - U.S. Markets open in 4 hrs 17 mins


% | $
Click the to save as a favorite.

OncoGenex Pharmaceuticals, Inc. Message Board

  • bagholderzunite bagholderzunite Nov 19, 2013 11:13 AM Flag

    "Considerably More Stringent"


    Is ~.02 at a 75% of events interim Considerably More Stringent than ~.05 at 100%.

    For this trial (my model -- near linear curves), the difference between those two measures is about 1.5 months (call it 5.5 month MST spread at the former, 4 month MST spread at the latter -- HR of ~.79 vs HR of ~.84).

    Is that Considerably More Stringent (CMS)? I dunno. Doesn't feel like it.....

    At the Avii interim level (~.0003), we're talking a not quite 9 month MST spread and an HR of ~.695. That is CLEARLY CMS.

    One thing I've learned NOT to do is take a CEO's adjectives at face value. We can't have any idea how to translate those three words into thresholds.

    SortNewest  |  Oldest  |  Most Replied Expand all replies
3.02-0.06(-1.95%)Jul 31 3:59 PMEDT

Trending Tickers

Trending Tickers features significant U.S. stocks showing the most dramatic increase in user interest in Yahoo Finance in the previous hour over historic norms. The list is limited to those equities which trade at least 100,000 shares on an average day and have a market cap of more than $300 million.
Tesla Motors, Inc.
NasdaqGSThu, Jul 31, 2014 4:00 PM EDT
eHealth, Inc.
NasdaqGSThu, Jul 31, 2014 3:59 PM EDT