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NanoLogix Inc. Message Board

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  • the_rail_splitter the_rail_splitter Feb 14, 2012 2:23 PM Flag

    NNLX BNF Rapid Detection verse Culture (Gold Standard)

    In parents' post this fact was pointed out:

    "First, he pointed out that the experiment was designed to determine sensitivity to Clindamycin rather than GBS detection sensitivity, per se."

    So, interpret what I said here with caution as I do not know exactly how this relates to AST testing--- at first I was interpreting it as overall GBS sensitivity and specificity, but am not sure if this is the case.

    Could really use the help of a medical professional in the interpretation. Perhaps parents could get the Swiss friend onto this board.

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    • rail...see my message to you on messenger; thanks

      • 1 Reply to parentsgratae
      • Hi All ;
        I think this link will be instructive.
        It is a paper comparing PCR to petri dishes, around page six (6), it compares the petri dish and PRC results. The PRC identified more then the petri dish, as does the Nanologix petri dish.

        Below is from the paper.

        Table 4. Group B Streptococcus agalactiae prevalence in 221 pregnant women admitted in labor considering two methodological
        Anatomical site of specimen collection
        by swab and prevalence
        Classical microbiological Genetic detection of GBS in
        method for GBS isolation the enrichment culture
        Vaginal 7 (33.4%) 32 (44.4%)
        Anorectal 10 (47.6%) 16 (22.2%)
        Both sites in the same patient 4 (19%) 24 (33.4%)
        Total of GBS colonized patients 21 (100%) 72 (100%)
        Estimative of GBS prevalence 9.5% 32.6%

        Here is the complete paper.

        Only my opinion.

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