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  • jacosa jacosa Feb 23, 2011 10:17 PM Flag


    There are a lot of details to conducting a study to support US registration. An investigator-sponsored trial not conducted with a view toward this goal is unlikely to be able to stand alone.

    And as always, the initial success and subsequent failure of both NAC and overnight hydration make it imperative that a preventive measure against CIN have multiple independent confirmations of its effectiveness.