I believe that is what makes the market problematic and subject to wild swings, expectations (another way of providing HOPE). Whatever the revenue in the future holds, NO ONE knows for sure. It is wiser to remain silent (although it doesn't do much for short term share price and may even ruin it) than to paint a rosey picture and disappoint.
Side note: Walt, did you have your hand in this: "An anticancer C-Kit kinase inhibitor is reengineered to make it more active and less cardiotoxic J. Clin. Invest. 2007 117: 4044-4054." - I'm still trying to figure out their methodology. Its not clearly stated in the original manuscript (I'm trying to dig up its referenced materials).