Nanosphere’s patent portfolio is comprised, on a worldwide basis, of 151 issued patents and 52 pending patent applications which we own directly or for which we are the exclusive licensee. Some of these patents and patent applications derive from a common parent patent application or are foreign counterpart patent applications and relate to similar or identical technological claims. The issued patents cover approximately 11 different technological claims and the pending patent applications cover approximately four additional technological claims. Many of Nanosphere's issued and pending patents were exclusively licensed from the International Institute for Nanotechnology at Northwestern in May 2000, and they generally cover Nanosphere's core technology, including nanotechnology-based biodiagnostics and biobarcode technology. In addition, as of December 31, 2010, we have non-exclusive licenses for at least 47 U.S. patents that cover 12 different technological claims from various third parties.