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ImmunoGen, Inc. Message Board

  • gunter.strobel gunter.strobel Nov 10, 2013 7:21 AM Flag

    IMGN901 target problem?

    I think they had "only" a target problem with IMGN901:

    IMGN901 is an ADC for the treatment of CD56 positive cancer. But a subtype of natural killer cells also regonized CD56.

    So, i think, IMGN901 kills cancer zells AND a subtype auf natural killer cells. So the patients are in trouble with infections.

    And on the other side, I THINK, immunogen use two or three types of linkers : smcc (Kadcyla, IMGN 289), spp, spdb (IMGN901)

    Sentiment: Buy

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