The well-informed and well-intentioned -- Listen to them, follow them. They are good and wise.
The well informed and ill-intentioned -- Beware of them. They are knowledgeable but mean.
The ill-informed and well-intentioned -- They are good. Unfortunately, they often follow the well-informed and ill-intentioned.
The ill-informed and ill-intentioned. Beware of them. They are both ignorant and mean.