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Elan Corporation, plc Message Board

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  • rslndmcln rslndmcln Mar 20, 2005 7:24 PM Flag

    MS Patients Want Pills Not Needles?

    I'm an MS patient.

    I found the statement by Neuro1111 interesting in regards to some of his patients favoring a pill over injections or infusion because it is more convenient.

    Actually one of the "selling points" for Tysabri was that it was "more convenient" than daily, every other day, or weekly injections (depending on what your injectible is.)

    Since it was a once a month infusion, much of the info I read stressed that a once a month infusion would be more convenient than injectibles, of course, it's efficacy rate was mentioned also, but the convenience of only having to have an infusion once a month was stressed.

    I, personally, don't find my interferon shots (I take Betaseron, so they're every other day) to be inconvenient. Takes me about 3 minutes and I take them right before bedtime. I don't have side effects, so that might be why I feel that way, and my MS is stable on the Beta, so I was taking a wait and see attitude toward the Tysabri.

    What's convenient to one person may not be convenient to another. Having to go to an infusion center or doctor's office once a month seems much more inconvenient to me than just injecting myself every other day in my own home.

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    • Why would you take something that is only
      50% as effective. Assuming mono Ty is safe
      (and I believe the facts point to that) I
      think you are in the minority of MS patients.

      MS, Chrohn's RA are all devastating diseases.

      It is inconceivable why somebody would choose
      something that is a whopping 50%+ less effective.

      • 2 Replies to elan2sixty
      • As far as efficacy and why I would take a med (Betaseron) that was less effective than Tysabri:

        Statistically, Betaseron (and the other interferons) have been shown to be 33 percent effective in reducing exacerbations.

        But that 33 percent is a mean. Some people will do better than 33 percent, some people will do worse.

        I evidently am one of those that, for now, am responding better than 33 percent to the medication in controlling my exacerbations and progression.

        So I know Betaseron is working for me.

        Now to the Tysabri, it has an effective rate of 66 percent in reducing exacerbations, but not all people will experience a 66 percent reduction. Some will have a better effectiveness, some worse.

        So why would I take the gamble to change meds, when what I am using is working just fine for me. I have no side effects (other than site reactions). I do not have to premedicate (with the interferons many premedicate with ibuprophen to control flu like side effects, with tysabri, many are premedicating with benadryl in case of allergic reaction), and I find it very easy to comply with my chosen treatment.

        Efficacy rate is not a guarantee that a particular drug will be better for a given individual who is not experiencing problems with the current therapy, and whose disease is being controlled by the current therapy.

      • Which part of his/her MS is stable and he/she is not experiencing any side effects didn't you understand? Rule of thumb is if it ain't broke, then don't fix it!

        Is he/she the typical patient on IFN? Not really

 

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