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Elan Corporation, plc Message Board

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  • elan2sixty elan2sixty Mar 20, 2005 7:46 PM Flag

    MS Patients Want Pills Not Needles?

    Why would you take something that is only
    50% as effective. Assuming mono Ty is safe
    (and I believe the facts point to that) I
    think you are in the minority of MS patients.

    MS, Chrohn's RA are all devastating diseases.

    It is inconceivable why somebody would choose
    something that is a whopping 50%+ less effective.

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    • As far as efficacy and why I would take a med (Betaseron) that was less effective than Tysabri:

      Statistically, Betaseron (and the other interferons) have been shown to be 33 percent effective in reducing exacerbations.

      But that 33 percent is a mean. Some people will do better than 33 percent, some people will do worse.

      I evidently am one of those that, for now, am responding better than 33 percent to the medication in controlling my exacerbations and progression.

      So I know Betaseron is working for me.

      Now to the Tysabri, it has an effective rate of 66 percent in reducing exacerbations, but not all people will experience a 66 percent reduction. Some will have a better effectiveness, some worse.

      So why would I take the gamble to change meds, when what I am using is working just fine for me. I have no side effects (other than site reactions). I do not have to premedicate (with the interferons many premedicate with ibuprophen to control flu like side effects, with tysabri, many are premedicating with benadryl in case of allergic reaction), and I find it very easy to comply with my chosen treatment.

      Efficacy rate is not a guarantee that a particular drug will be better for a given individual who is not experiencing problems with the current therapy, and whose disease is being controlled by the current therapy.

    • Which part of his/her MS is stable and he/she is not experiencing any side effects didn't you understand? Rule of thumb is if it ain't broke, then don't fix it!

      Is he/she the typical patient on IFN? Not really


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