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Mast Therapeutics, Inc. Message Board

  • serenityloveh69@att.net serenityloveh69 Sep 1, 2013 10:11 PM Flag

    Well.... 0.0166 cents presplit of that 1:25 r/s . A r/s comp of over 1:5 rarely makes it. The snake oil king Won't

    Now how will admit that the old snake oil wood factory has done good . Better yet man up and admit if you didn't sell last year in Augest

    Sentiment: Strong Sell

    SortNewest  |  Oldest  |  Most Replied Expand all replies
    • no no rs ha ha.

    • thebigmonkey@sbcglobal.net thebigmonkey Sep 26, 2013 7:14 PM Flag

      The need for another r/s is in line...but whats new

      Sentiment: Strong Sell

    • serenityloveh69@att.net serenityloveh69 Sep 6, 2013 11:48 AM Flag

      Truth up

      Sentiment: Strong Sell

    • no rs you wish

    • serenityloveh69@att.net serenityloveh69 Sep 4, 2013 2:26 PM Flag

      Truth up

      Sentiment: Strong Sell

    • Google Finance....Institutional Ownership Info
      OWNERSHIP INFORMATION
      Shares Outstanding 102.71 Mil
      Institutional Ownership (%) 47.79
      Top 10 Institutions (%) 41.81
      Mutual Fund Ownership (%) 6.50
      5%/Insider Ownership (%) 25.88
      Float (%) 99
      OWNERSHIP ACTIVITY
      DESCRIPTION # OF HOLDERS SHARES
      Total Positions 27 49,267,826
      New Positions 20 41,504,321
      Soldout Positions 4 565,778
      Net Position Change 7 3,076,045
      Buyers 5 3,558,585
      Sellers 2 -482,540

      INSTITUTION NAME SHS HELD SHS CHG %CHG $CHG* %OUT %PORT RPT DATE
      Franklin Advisers, Inc. 10,987,000 10,987,000 NA 4,716,000 10.7 0 06-30-13
      Sabby Management LLC 7,711,867 7,711,867 NA 3,310,000 7.51 0.22 06-30-13
      Great Point Partners LLC 5,800,000 5,800,000 NA 2,490,000 5.65 1.97 06-30-13
      Deerfield Management Co 3,948,302 3,948,302 NA 1,695,000 3.84 0.08 06-30-13
      Alyeska Investment Grp, LP 3,800,000 3,800,000 NA 1,631,000 3.7 0.08 06-30-13
      Millennium Mgmt LLC 3,000,000 3,000,000 NA 1,288,000 2.92 0 06-30-13
      Pine River Capital Mgmt, LP 2,578,486 1,953,486 312.56 837,916 2.51 0.02 06-30-13
      Ancora Advisors LLC 1,848,045 973,045 111.21 417,536 1.8 0.14 06-30-13
      Vanguard Group, Inc. 1,700,681 613,118 56.38 263,175 1.66 0 06-30-13
      Deutsche Bank AG 1,564,707 1,564,707 NA 671,000 1.52 0 06-30-13
      Columbia Mgmt Invt LLC 1,200,000 1,200,000 NA 515,000 1.17 0 06-30-13
      Fidelity Mgmt and Research 1,048,304 1,048,304 NA 450,000 1.02 0 06-30-13
      GRT Capital Partners LLC 894,401 -482,427 -35.04 -207,124 0.87 0.08 06-30-13
      UBS O'Connor, LLC 794,900 794,900 NA 341,000 0.77 0.01 06-30-13

    • serenityloveh69@att.net serenityloveh69 Sep 3, 2013 2:12 PM Flag

      Very understandable too

      Sentiment: Strong Sell

    • serenityloveh69@att.net serenityloveh69 Sep 3, 2013 10:35 AM Flag

      Truth up

      Sentiment: Strong Sell

    • Part 4

      MST-188 for Sickle Cell Disease

      Patients with SCD are known to experience severely painful episodes associated with the obstruction of small blood vessels by sickle-shaped red blood cells. These painful episodes are commonly known as acute crisis or vaso-occlusive crisis. Reduced blood flow to organs and bone marrow during vaso-occlusive crisis not only causes intense pain, but can result in tissue death, or necrosis. In previous clinical studies of SCD, MST-188 has demonstrated the ability to restore microvasular function, reducing pain, as well as decreasing the duration of the vasco-occlsive crisis.

      Previous Phase 3 Study

      In 2001, SynthRx, before its acquisition by MSTX, published the results of the Phase 3 study evaluating MST-188 for the treatment of SCD in the Journal of the American Medical Association. The study found that those who received MST-188 experienced a decrease in the duration of painful episodes and experienced fewer symptoms when compared to those only receiving placebo. The difference between these groups was significant, but relatively small. In subgroup analysis, a more significant effect on both parameters was observed in children and in patients who were receiving concomitant hydroxyurea. Additionally, the researchers concluded that MST-188 was safe and well tolerated.

      In reviewing their findings and study design, the investigators concluded that they made serious missteps when establishing the primary endpoint of the study. The use of an extremely stringent definition of crisis resolution (168 hours) represented a very conservative approach to the analysis of the data. As the 2001 article stated:

      "It is important to emphasize that in an earlier Phase II study, even greater benefits had been observed. This disparity may be explained in part by the assumptions used in our definition of crisis duration, the primary endpoint in the study. Specifically, we observed that fewer patients achieved crisis resolution within 168 hour

      Sentiment: Strong Buy

    • serenityloveh69@att.net serenityloveh69 Sep 1, 2013 11:12 PM Flag

      Basically looks to be really bad ** Warning **

      MSTX Composite Indicators Signal
      TrendSpotter Sell

      Short Term Indicators
      7 Day Average Directional Indicator Sell
      10 - 8 Day Moving Average Hilo Channel Hold
      20 Day Moving Average vs Price Sell
      20 - 50 Day MACD Oscillator Sell
      20 Day Bollinger Bands Hold

      Short Term Indicators Average: +60.00%% Sell
      20-Day Average Volume - 732

      Medium Term Indicators
      40 Day Commodity Channel Index Sell
      50 Day Moving Average vs Price Sell
      20 - 100 Day MACD Oscillator Sell
      50 Day Parabolic Time/Price Sell

      Medium Term Indicators Average: +100.00%% Sell
      50-Day Average Volume - 561

      Long Term Indicators
      60 Day Commodity Channel Index Sell
      100 Day Moving Average vs Price Sell
      50 - 100 Day MACD Oscillator Sell

      Long Term Indicators Average: +100.00%% Sell
      100-Day Average Volume - 536

      Overall Average: +88.00%% Sell

      Average to consider is .25 cents

      Sentiment: Strong Sell

 
MSTX
0.582-0.008(-1.36%)Sep 18 4:01 PMEDT

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