IF the FDA approves Aveed chances are sales will surpass expectations. The key word is COMPLIANCE. Patient may stick around taking a shot every 3 months instead of skin applications every day. The vast majority of latter(around 80%) discontinue treatment early on. Quality of sex life will improve dramatically on Aveed (Libido increases also which Viagra et al can't deliver). I think an achy butt for a few days is something patients can live with..