"Behold,Damascus is taken away from being a city, and it shall be a ruinous heap." (Isaiah 17:1)
It should be noted that the 5,000 year-old city of Damascus is the world's oldest perpetually inhabited city. However, according to the prophet Isaiah, Damascus will be "taken away from being a city" and be turned into a "runious heap." This has never happened before in all of history, but has been reserved as a sign of the end-time, unfolding biblical scenario.