This is pure speculation, SNSS is seeking partnership with Japan, a few reasons:
1) Japan population is getting old, old people population would give benefit for AML,
2) Remember that year ago the earth quake, which got Japanese lot of radiation of Nuclear power
3) Yuan is pretty strong now, if they invest now, later on the depreciation would make it beneficial too.
Just my $.02, I suspect that PPS should be at least $10. Do your own DD
At the last investor road show, Dan and or Eric mentioned that they were in talks with a potential Japanese partner, due to a b....h of a Japanese regulatory environment. It's probably Takeda , due to SNSS's relationship with a Takeda subsidiary, in the States. Radiation worries?! Hell yes! Increased cancer rates?! Probably, but we won't know for awhile. Yuan is the Chinese currency. Yen is used in Japan, but you are right about the currency strength and demographic implications.