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Shire plc Message Board

  • stiilbelieve42 stiilbelieve42 Apr 12, 2007 8:27 AM Flag


    of OLGC with my dndn profits, 'cause of cash in hand, no debt, own their real estate, and pps is only 1.60.
    It will change though.
    Why? Their product is safe, effective, and badly needed by the elderly for their non healing fractures.
    Just read below and you'll understand why.

    The study was a prospective, double-blind, randomized, placebo-controlled Phase 3 clinical trial designed to evaluate the safety of Chrysalin and its efficacy regarding the rate of healing in adult subjects with unstable and/or displaced distal radius fractures.
    Subjects were stratified by bone density score (T-score, determined by DXA scan) and grouped as normal, osteopenic, or osteoporotic. One hundred fifty seven female subjects were characterized as osteopenic. A statistically significant effect was observed with Chrysalin treatment in the primary endpoint, time to immobilization removal (p = 0.033). Another clinically relevant endpoint, time to clinical evaluation of healing, also showed a significant effect of Chrysalin treatment (p = 0.015). Radiographic evaluation of this osteopenic female population showed statistically significant differences between the Chrysalin-treated and placebo subjects for two of three radiographic parameters measured: time to radial cortical bridging (p = 0.022) and time to overall radiographic healing (p = 0.0028).

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