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Dendreon Corporation Message Board

  • anderbest18 anderbest18 May 8, 2010 6:13 AM Flag


    - 50 Million cash on hand. Total $10 billion sales potential.

    -CANCER VACCINE: AEZS-120 cancer vaccine similar to Dendreon’s provenge. Phase I to begin mid-to-end 2010

    -PHASE 3 TRIALS: 4 Phase 3 cancer trials in 2010:

    1) AEZS-130 (SolorelTM) Diagnostic Adult Growth Hormone Deficiency trial. Filing of U.S. NDA planned after study completed later this year.
    2) Perifosine, Multiple myeloma Cancer.
    3) Perifosine, Refractory Advanced Colorectal.
    4) AEZS-108, Ovarian Cancer.

    AEZS could initiate also Perifosine phase III for treatment of Kidney Cancer. That would make it FIVE phase III cancer trials.

    Final results of a randomized phase II study of perifosine in combination with capecitabine (P-CAP) versus placebo plus capecitabine (CAP) in patients (pts) with second- or third-line metastatic colorectal cancer (mCRC) are to be Presented by Donald Richards.

    PARTNERS: AEterna stated publicly they are looking for partners, news could come at any time.

    AEZS pipeline:
    Perifosine (phase III/KERX partner)
    Multiple Myeloma
    Advanced Colorectal Cancer
    Kidney Cancer and Others
    AEZS-108 (phase II)
    Endometrial Cancer
    Ovarian Cancer
    Other Cancers
    AEZS-112 (phase I)
    Solid Tumor
    AEZS-120 *Tumor Vaccine (pre-clinical **hello DNDN)
    Prostate Cancer
    AEZS-129/131PI3K/ErkInhibitor (pre-clinical)
    (Marketed by Merck Serono, Nippon Kayaku / Shionogi (Japan))
    In VitroFertilization
    AEZS-130 (SolorelTM) - Phase III
    Diagnostic –Adult Growth Hormone Deficiency
    AEZS-130 (macimorelin) - Phase I
    AEZS-123Ghrelin Antagonist - Preclinical

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