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Vertex Pharmaceuticals Incorporated Message Board

  • nhayden9 nhayden9 Nov 18, 2003 11:05 AM Flag

    MorganStanleyDW Technician comment

    Rick Bensignor(technician) today in his conference call said that
    "there is no reason to own this stock even at $9.."
    So bottom feeders you gotta wait maybe till good news or $5. Maybe by then Vicki and Josh have fattened up their checking accounts and will stop selling.
    I am not short this stock.
    Longs,take your tax losses now. Buy in Jan

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    • It never ceases to amaze me how a bunch of naysayers come out of the woodwork to put down a company and its leaders when any sort of a setback occurs.

      The recent setback is not as severe as one should believe. The drug showed tox levels in a long term high dosage tox study... but not in a shorter term and lower tox study. The amount of drug that was administered (in animals) was equivalent to a human eating pounds of it per day for a long time... of course something would show up in liver studies... when you do a tox study you expect to see tox.

      The setback isn't that the drug isn't viable its that it will be delayed... delayed is important but not some death nail to VRTX. The VRTX pipeline is still impressive and this specific drug will eventually come to fruition.

      I believe in VRTX.

      What a bunch of naysayers.

      • 2 Replies to terawatcher
      • True we are bashers but Josh deserves it.
        He shoulda done an acquisition like MLNM when his stock was high.
        My advice stands, sell, take a tax loss then buy in again in January if you still like VRTX. The price is unlikely to soar to 15 in the meantime.

      • tera,
        <<The amount of drug that was administered (in animals) was equivalent to a human eating pounds of it per day for a long time... of course something would show up in liver studies... when you do a tox study you expect to see tox. >>
        ----------
        Naturally the toxicity test is designed to see the effects of high dosages. However are you saying that the animal dosage was much higher than the typical required toxicity test? Has there been any info about how the animal dosage translates into human dosage.

        Was the dosage decided by Aventis extraordinarily high to purposely get a high toxicity result so that Aventis could renegotiate the roylty terms? Of course that does not make sense but I wonder. Do not accuse me of conspiracy theory fantacy because I have recently read that several big pharmas are trying to find excuses to renegotiate the collaboration terms with their smaller biotech partners thinking that the smaller companies do not have any choice but to accept less royalties than previously agreed upon due to their short supply of cash and the difficult environment to raise cash.

        Ps. This also reminds me of the fact that when the first Pralnacasan study was done and the results were announced Boger and Sato kept insisting that the study proved that the end points were successfully met. However Aventis would not concur and delayed the follow up of the project for many months to "study and further analyze the results." I wonder if they have been a half-hearted partner all along?

    • Thank you for your sage advice. I would have never thought an objective and altruistic person like you would come along and try to save the longs from impending doom. Nyuk! Nyuk!

 
VRTX
91.30-0.62(-0.67%)Aug 20 4:00 PMEDT

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