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Vertex Pharmaceuticals Incorporated Message Board

  • Isaac_dj Isaac_dj Feb 7, 2006 4:53 AM Flag

    VX-950 -- 100% EFFICACY IN HepC !!!

    IN ALL PATIENTS, VIRAL RNA WAS UNDETECTABLE after 28 days, and NO SERIOUS ADVERSE EVENTS were reported.

    "There were no treatment discontinuations and NO SERIOUS ADVERSE EVENTS reported...

    Preliminary HCV RNA results in patients for weeks 2-4 are as follows:

    *** At the end of week 2, plasma HCV RNA was below the limit of quantitation (30 IU/mL) in 11 of the 12 patients; and undetectable (less than 10 IU/mL) in three of 12 patients.

    *** At the end of week 3, plasma HCV RNA was below the limit of quantitation (30 IU/mL) in 12 of the 12 patients; and undetectable (less than 10 IU/mL) in nine of 12 patients.

    ***** At the end of VX-950 dosing (end of week 4; day 28), PLASMA HCV RNA WAS UNDETECTABLE (less than 10 IU/mL) IN ALL 12 PATIENTS.

    **** No patients showed evidence of viral breakthrough while on treatment."

    Again, at the end of VX-950 dosing (end of week 4; day 28), PLASMA HCV RNA WAS UNDETECTABLE IN ALL 12 PATIENTS. (!!)

    NO ONE CAN BEAT AN EFFICACY LEVEL OF 100% particularly when NO SERIOUS ADVERSE EVENTS were reported.

    FDA APPROVAL OF VX-950 is NOW inevitable and the dominance of VX-950 in the LARGE BLOCKBUSTER MARKET of HepC IS ASSURED.

    It will all be history soon.

    http://biz.yahoo.com/prnews/060207/netu005.html?.v=47

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    • << IN ALL PATIENTS, VIRAL RNA WAS UNDETECTABLE after 28 days, and NO SERIOUS ADVERSE EVENTS were reported.

      "There were no treatment discontinuations and NO SERIOUS ADVERSE EVENTS reported...

      *** At the end of week 3, plasma HCV RNA was below the limit of quantitation (30 IU/mL) in 12 of the 12 patients; and undetectable (less than 10 IU/mL) in nine of 12 patients.">>

      I DON'T THINK WALL STREET HAS GRASPED YET WHAT 100% EFFICACY IN HepC MEANS.

      It means that VRTX will either have HUGE REVENUES, or BE ACQUIRED AT A VERY FAT PRICE.

      The point is that VRTX should have been UP 20% on the news but by the rate so far, we may end up with a GAIN OF just 10% today. As a result, the SHARP RISE IN VRTX WILL CONTINUE. The longer-term rally in VRTX is expected to last for several years, periodically fueled by OUTSTANDING TRIAL RESULTS, new discoveries, and SUBSTANTIAL REVENUES (if VRTX is not acquired).

      Again, NO ONE CAN BEAT AN EFFICACY LEVEL OF 100%, particularly when NO SERIOUS ADVERSE EVENTS were reported.

      It will all be history soon.

    • WOW!
      Nothing else to add.

 
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