Observe that a priming full dose of SOC is given to the first two Arms for 4 weeks prior to the start of SGP's triple combo of duration 24 or 44 weeks. If PROVE 1 had started with such a priming dose for 4 weeks, the PCR values would be certainly higher than we got without it. If the competing two drugs are compared to two sprinters in a race, their PI jumped the gun. It cheated. It is ironic that the trial is known as SPRINT-1.