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Vertex Pharmaceuticals Incorporated Message Board

  • johnf50@rocketmail.com johnf50 May 7, 2012 9:48 AM Flag

    Sweat Chloride

    Third or Verity -

    Setting aside the 20 or so posts this morning by the shorts screaming this is going back down - because they are taking a bath...

    Would the two of you care to elaborate on the science of sweat chloride vs lung function.

    My science base is no where near the two of you... my humble take is that the lung function would be a predecessor indicator to sweat chloride... so the dynamic we are missing here is time.

    So 30 to 60 days on treatment and we see improvement in lung function... and over more time, sweat chloride levels come down, give a take 10 to 14 months of treatment.

    What do you think about my theory?

    Please by all means, I paraphrase into non layman's terms because I am a general contractor and real estate developer by trade. So blow holes, educate and enlighten.

    Thanks for your feed back.

    ~ JF

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