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Vertex Pharmaceuticals Incorporated Message Board

  • bootpart bootpart Nov 28, 2012 3:39 PM Flag

    My Gilead question was deleted too....who deletes these posts?

    The Gilead announcement showed 78% (?) cure at SVR12 and this seems a long way from the 100% cure previously announced. Also the 78% did not include Gen type 1. Yes it is oral and does not include interferon so that's good. But the cure rate will likely go down further at SVR24 and whenyou add Gen type 1. Does Wall St understand this or do they have their heads in the sand? Am I missing something? Potentially lower cure rate than Incivek although less side effects. Not the super pill I thought they had.

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    • You are correct that the 100% SVR was not achieved, but this is not surprising in larger studies. I would be surprised if the 78% drops by more than 1 or 2% (if at all) since the SVR12 timepoint is VERY predictive of SVR24 (lots of data that shows this) and without Peg on-board, it is is likely that anyone who would have relapsed would have done so before the 12 week follow-up visit (Peg has a longer half-life than the orals). I would say the result is only disappointing if you are a perfectionist. It is still a very admirable result and great for the patients. I have no monetary interests. Good luck to everyone!

      • 1 Reply to yougottasayyes
      • understood. My beef is with how the company portrayed the medicine and how wall st jumped to 100% cure rate so quickly. In reality it will probably be somewhere in the 70s. So slightly worse the Incivek but without the rash. Good med but not as good as has been portrayed to date. Of course as happened with Incivek, if another Nuc a year or two behind GILD's has a better cure rate/oral/no rash then the doctors/patients will do exactly what they did with Incivek and start warehousing patients all over again.

    • I responded 3X and all have not gone to posts. They are either deleting or software is tagging some people or words and killing the posts. Analysts see what they want. Now GILD is king. Wish VRTX mgt came out and said something about the data but no, they praise GILD in their investor conferences. That dope has to be fired. Just hope VRTX doesn't buy out SRPT as it's flying on rumors vrtx is buying them. I don't want more junk. VRTX is enough

    • I responded 3X and all have not gone to posts. They are either deleting or software is tagging some people or words and killing the posts. Analysts see what they want. Now GILD is king. Wish VRTX mgt came out and said something about the data but no, they praise GILD in their investor conferences. That dope has to be fired. Just hope VRTX doesn't buy out SRPT as it's flying on rumors vrtx is buying them. I don't want more junk. VRTX is enough

    • I responded 3X and all have not gone to posts. They are either deleting or software is tagging some people or words and killing the posts. Analysts see what they want. Now GILD is king. Wish VRTX mgt came out and said something about the data but no, they praise GILD in their investor conferences. That dope has to be fired. Just hope VRTX doesn't buy out SRPT as it's flying on rumors vrtx is buying them. I don't want more junk. VRTX is enough.

    • analysts just see what they want to see. I just hope VRTX doesn't buy out SRPT as it's flying high on rumors vrtx will buy them out. I don't want more junk to own. VRTX is enough.

    • I reaplied and yahoo cut it. LOL. bunch of losers there too.

      • 2 Replies to chevymalibu1966
      • Since yahoo's major fiasco with the new rules to antagonize those who use its message board, I do the following:

        1. I always copy my typed post, before I click on the post button so I do not have to retype in case yahoo sensors my post.

        2. If they sensor it, I paste the message again and go to the preview page and post it from there. It worked for me one time before.

        3. In case that trick does not work, you need to modify some of the words in your post. Omit quotation marks especially for long phrases. Do not type any lin ks or use words like cl ick,
        brow ser, , goo gle etc--words that provoke the sensor software to flag your post for elimination. I believe Yahoo wants to prevent any info that promotes competition to it products and services. As I have done in the previous sentence, if you need to use some words that may provoke the sensor software place spaces in the middle of the words. Also Change the title of your message. If you have to give info about a li nk give only key word in separate format and keep try various ways because the software seems to recognize camouflaged words that are part of a li nk.

        4. Sometimes if you are posting a new post and it won't let you, try it as a reply to an existing post with a short explanation as to why you are doing that.

        I suggest that if we all try any new tricks that work, we should post it for the benefit of fellow posters.

        Unfortunately, Yahoo has a De Facto monopoly of financial message boards. In authoritarian systems they could be forced to stop abusing their customers. But under democracy that can not be done.

      • I responded 3X and all have not gone to posts. They are either deleting or software is tagging some people or words and killing the posts. Analysts see what they want. Now GILD is king. Wish VRTX mgt came out and said something about the data but no, they praise GILD in their investor conferences. That dope has to be fired. Just hope VRTX doesn't buy out SRPT as it's flying on rumors vrtx is buying them. I don't want more junk. VRTX is enough

 
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