Hard to be optimistic about the fact that the results promised by the end of 2012 haven't been announced. I assume no news = bad news. Can anyone think of a realistic scenario (preferably with a comparable example at another biotech) which could see this delay followed by good news?
sometimes it takes time to analyze the results but my guess is if it was great (good p value), they'd be out now and a press release on the goodyear blimp. It must be marginal or they are digging into the data to say some signal in the 2ndary measures was tickled. Overall, we won't know as who knows what's going on inside. Also, it's the holidays and they might be waiting for january. insiders know but they don't post here.
In the spirit of offering what may have been forgotten or never known, Vertex management was extremely "burned" at midyear when it released fast, "top line" results on the 809/Kalydeco trial that it thought was "material" only to have a miscommunication at the detail level force a subsequent embarassing partial retraction. I know a poster would never intentionally "forget" an important event just to bolster their viewpoint so this reminder is simply to offer my opinion that management is simply, tho perhaps reactively, playing it cautiously with 787.