congratulations to all longs.
If VRTX wants to see me happy, I want progress in VX 787. Flu bug is an evil and if this is truly a drug that works 4 days after the inoculation, we should not waste time.
Study 102 has cohort 4 which as finished recruiting heterozygous delta F 508. They are testing Lumacaftor 400 mg PO bid dosing with ivacaftor 250 mg PO bid. They are looking at FEV1 changes. I don't remember any one talking about this. When they did cohort 3, it was only for pk/pd. They are not waiting for a second generation correctors, they are shooting at hetozygous bird with an old AK.