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Vertex Pharmaceuticals Incorporated Message Board

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  • skinKhound skinKhound May 7, 1998 7:37 AM Flag

    huge increase in short interest

    clinician. If the anti-helicase stuff is anything
    like integrase inhibitors I suspect that PI will reign
    for hep c as well. the integrase inhibitors have
    delivery problems etc. But i'm not sure what's been done
    with that. I think, though, that the extensive
    experience with protease, and demonstrable efficacy in
    another virus (HIV), should push that program along.
    Educate me....

    Of course, anything for hep C will
    be a blockbuster if it's even 25% helpful given the
    cost and toxicity of interferon and ribavirin (just
    approved)....which is maybe 50% effective. Cheers-I'll bone up on
    helicase so we can have a better discussion.


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