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  • garydaemon garydaemon Oct 10, 2013 6:13 AM Flag

    GSK2606414 news today

    Interesting news out today:
    Kings College London
    The Medical Research Council (MRC) team focused on the root cause of many degenerative brain diseases, including Alzheimer's and Parkinson's - abnormally shaped proteins that stick together in clumps and fibres.

    When enough misshapen protein builds up in the brain it can trigger a reaction that results in the death of nerve cells.

    Other approaches have sought to stop or limit the accumulation of the abnormal protein, whose structure is folded the wrong way. Instead, the MRC researchers targeted the harmful way brain cells react to misfolded proteins.

    Using a drug injected into the stomachs of mice through a mouth tube, they flipped a cellular switch from "off" to "on" to prevent neurons dying.
    Dr Clare Walton, from the Alzheimer's Society, said: "What we need now is further research into potential drugs which can target the same pathway.

    Sentiment: Buy

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