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Fibrocell Science, Inc. Message Board

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  • dmesshian dmesshian Sep 9, 2011 1:41 PM Flag

    ***OOPS U.K wakes up to LAVIV Not Good, Must Read!***

    I commented, that the following observation came from doctors who used Laviv for the 6 years it was on the market in Europe.

    *****‘Most of the women who looked to Isolagen for skin rejuvenation were in their 50s,’ he says. ‘But, as you get older, you have fewer active fibroblasts. As a result, you tend to have less raw material to work with. Things like this aren’t one size fits all.’

    Other doctors I spoke to agreed. They felt that the treatment had potential and, while they doubted its ability to tackle deep lines, agreed it had shown good results in young patients. They even suggested one of the most efficacious ways of using the technology would be for women in their 20s to bank their healthy fibroblasts with a view to using them for skin rejuvenation at a later date. *******

    Mukenaki's response: *******"Have you gotten stupider by the minute?"
    >>>>>>>>>>>>>

    Well, if I was getting "stupider" by the minute, what would you say about the choices of the researchers whose data led them to the decision that the "highest yield" and best quality of "human collagen" was obtained from samples extracted new born infants? They concluded infant fibroblast, like in stem cell research, was healthiest, most active, and produced greatest yield of human collagen.

    If the performance of the various samples were equal, why would they go through all the trouble and expense to obtain such samples, when -- as you "categorically stated -- all fibroblast yielded the same results, irrespective of age.

    Yet, the response from the Laviv researchers was less agreeable and supportive of your position by their following answer:

    *******After leafing through the 94-page dossier its makers presented to the FDA, and exchanging countless emails with the company, it seems that the answer is: no. While it believes that the idea of storing young cells ‘is an interesting concept, at this time that concept has not been clinically tested’ so it ‘cannot comment further’.
    Instead, on the basis of clinical tests that show although this treatment will not always work in 100 per cent of patients, it continues to claim that Laviv can be used to treat any adult over the age of 18. One can only hope that U.S. consumers will learn from their UK counterparts...********


    Read more: http://www.dailymail.co.uk/femail/article-2031144/As-latest-anti-ageing-wonder-treatment-hits-U-S-autumn-investigate-new-Botox-puffed-be.html#ixzz1XTgfIgce

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    • ****dmesshian: "I commented, that the following observation ..."

      Oops, my comments were to spliff4joy who vehemently denied to be you as seen below. Are you pretending to be spliff4joy? Who was lying here, you spliff4joy or you dmesshian? LOL.

      http://messages.finance.yahoo.com/Business_%26_Finance/Investments/Stocks_%28A_to_Z%29/Stocks_F/threadview?bn=109334&tid=11003&mid=11201

      ****spliff4joy/dmesshian: "Mukenaki's response: *******"Have you gotten stupider by the minute?""

      And, that is absolutely correct. You couldn't even keep your aliases straight never mind scientific matters. More on the later below.

      ****spliff4joy/dmesshian: "when -- as you "categorically stated -- all fibroblast yielded the same results, irrespective of age."

      I challenge you to come up with that quote in any of my posts. It does not exist.

      But your ignorance shows as you do not understand that "senescent fibroblasts still work" even if "young fibroblasts work better". Your reasoning goes like this: "infant stem cells work best" and "older stem cells don't work as well as infant stem cells", therefore, "older stem cells don't work". No need to comment further on the prowess of your reasoning ability or the lack of it.

      The data that the FDA used to approve laViv were obtained on patients with minimum age 40 ranging up to 80's. 60% of them were between 50 and 65 and 21% older than 65. It is absolutely true that laViv works on older patients.

      Now let me explain what Dr. Inglefield and others said once and for all so you won't bring up this canard again.

      What Dr. Inglefield said was this: "‘But, as you get older, you have fewer active fibroblasts. As a result, you tend to have less raw material to work with." That is correct. And, that is why FCSC takes the trouble to grow fibroblasts ex vivo to ensure that an adequate number of healthy cells will be available on injection.

      Then, other doctors "suggested one of the most efficacious ways of using the technology would be for women in their 20s to bank their healthy fibroblasts with a view to using them for skin rejuvenation at a later date." That is also correct. They were not suggesting young women in their 20's to use laViv. They suggested that the young cells should be saved for future use. Do you see the potential value of a long-term relationship between such patients and FCSC?

      • 1 Reply to mukenaki
      • Mukenaki's statement: "Then, other doctors "suggested one of the most efficacious ways of using the technology would be for women in their 20s to bank their healthy fibroblasts with a view to using them for skin rejuvenation at a later date." That is also correct. They were not suggesting young women in their 20's to use laViv. They suggested that the young cells should be saved for future use. Do you see the potential value of a long-term relationship between such patients and FCSC?"

        We finally agree on something! What a bonanza>
        We can infer from your statement that you "tacitly agree" that Laviv is not a treatment for the GRAND majority of WOMWEN OVER 30 YEARS OF AGE. It would be a waste of good money for women over 30 to pursue Laviv wrinkle treatment.

        I sure hope you stay true to your convictions and not change in mid-stream.

 
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